Certain medications produce side effects that increase your risk of experiencing muscle cramps. Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." About one-third of the U.S. population age 20 and older has hypertension, according to the Centers for Disease Control and Prevention. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. A muscle cramp (charley horse) is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. muscle cramps can also occur as a side effect of some drugs. Rest Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. There may be tenderness on touching the muscle with ones hands. There always is the sensation of a tense or tight muscle that feels very hard compared to other relaxed muscles. The pain is localized at the site of the muscle. Your doctor can show you stretching exercises that can help you reduce your chances of getting muscle cramps. Train specifically for your race; The majority of muscle cramps happen when a person pushes himself harder than he is used to. III. Delevett AF, Recalde M "Diuretic-induced renal colic." These medications, also known as water pills, can cause a number of side effects, including muscle cramps. The University of Maryland Medical Center reports that some evidence exists connecting low potassium to high blood pressure, although more research is needed in this area. Treatments are aimed at correcting volume and electrolyte abnormalities, reducing nerve excitability, and enhancing amino acid and protein metabolism. Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly.1 Their etiology is varied; most commonly, these cramps are idiopathic. Background: Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. This can make you tired or weak or give you muscle cramps or a headache. If you do not receive an email within 10 minutes, your email address may not be registered, If the pain is unbearable and persists for a long time, then it is better to consult a doctor. With the notable (and relatively rare) exceptions of serious electrolyte imbalances including hypokalemia, hypomagnesemia and hypocalcemia, these cramps are typically benign in nature. Some diuretics … You may experience frequent urination when you're on a diuretic, especially in the first few weeks, according to MayoClinic.com. Other possible side effects include lightheadedness, fatigue, bowel changes, and muscle cramps. Having a low potassium level can have serious health consequences. Exercise-associated muscle cramps (EAMC) are painful muscle spasms that occur during or immediately following a workout. The cramping is so bad that I am forced to use Spirivia instead. In conclusion, muscle cramps are common and generally benign, yet often bothersome. Salt. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. How they can cause leg cramps: Like short-acting loop diuretics (see above), thiazide diuretics can deplete key electrolytes, causing leg cramps and other serious muscle problems. I've taken Lasix for years and my potassium levels have been in the normal range when tested and when i get any type of muscle cramps i take a little bit of salt from the salt shaker and dissolve it in my mouth. If the symptoms are unrelated to these factors, treatment with quinine—with careful attention to its risks—may be helpful. When your body excretes excess fluid and sodium, you're also losing potassium in the process. Too-tight … Specifically, it is likely that cramps that occur in the course of diuretic therapy are attributed to electrolyte disturbances or volume contraction, and are treated accordingly, but not with quinine. You can usually treat muscle cramps with self-care measures. National Organization for Rare Disorders. Fluid, Electrolyte and Acid-Base Physiology. Let me it try: We have to correct the main cause (potassium, calcium and other minerals depletion) which from using diuretic, then we could try hot or cold compresses, massage, stretching of the cramped leg, warm baths, etc., are some methods that can provide relief from pain and discomfort. The mechanism of diuretic‐associated cramping (if such an entity truly exists) is likely related to hypokalemia, hypomagnesemia, or volume contraction (with or without metabolic alkalosis). Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. ; Sheldon G. Sheps, M.D. Low potassium may cause muscle cramps. Muscle Cramps and Diuretic Therapy Muscle Cramps and Diuretic Therapy Mosenkis, Ari; Townsend, Raymond R. 2005-02-01 00:00:00 Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly. Muscle cramps typically start in the leg—often in the calf muscles … The most important sign is intense pain caused by the extreme tightening of the muscle. She has a bachelor's degree in public health as well as a master's degree in English. P T. 2015;40(3):185–190. Medication Use and Functional Status Decline in Older Adults: A Narrative Review. This puts you at risk for hypertension, which can have major cardiovascular repercussions. Muscle Cramps in Old Adults: Clinical Features and Pathophysiology. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Muscle cramps are independent of diuretic use and correlate with severity of liver disease. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Clinical epidemiology of nocturnal leg cramps in male veterans, Prevalence and characteristics of muscle cramps in patients with varicose veins, Leg cramps in the elderly: prevalence, drug and disease associations, Meta‐analysis of efficacy of quinine for treatment of nocturnal leg cramps in elderly people. Hypokalemia. Men may occasionally experience erectile dysfunction. Updated January 23, 2017. 64. Journal of the American Geriatrics Society. Research about the benefits of apple cider vinegar for positive general health is … Journal of the Korean Geriatrics Society. Grunwald MH, Halevy S, Livni E "Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test." Nevertheless, they can be bothersome. Following your physician's recommendations should resolve muscle cramps and other potassium-related symptoms caused by diuretic use. Interestingly, potassium‐sparing diuretics, such as amiloride, are also associated with cramping. 63. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic Talk to your pharmacist to find out if any of the medications could be increasing your risk. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Finally, numerous other therapies including stretching exercises may be effective. JAMA 225 (1973): 992. can any docs explain? Previously working for the North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for over six years. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. In less than five minutes the cramps are gone. Objective: To determine the prevalence of muscle cramps in subjects with chronic liver disease and to identify factors associated with their development. Apple Cider Vinegar. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. Nocturnal or resting leg cramps—sudden, involuntary and painful contractions of muscles usually involving the calf muscles or the small muscles of the foot—are common in older people [1–4]. J Toxicol Clin Toxicol 33 (1995): 729-33. Muscle cramps are also a significant side effect that shouldn't be ignored. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic with another antihypertensive agent, but rarely with that other agent alone. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Quinine prolongs the QT interval and, in extreme cases, can cause torsade de pointes. and you may need to create a new Wiley Online Library account. Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men, https://doi.org/10.1111/j.1524-6175.2005.04094.x. In fact, the Physicians’ Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide-like indoline diuretic. If your feet are cramping, it’s possible that your shoes could be too tight. You may also be prescribed a different type of water pill. medications that can cause muscle cramps include: * furosemide (lasix), hydrochlorothiazide (microzide), and other diuretics … Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. How To Stop Muscle Cramps. Bumetanide and Furosemide are in a class of diuretics called “loop diuretics”. Another risk that is particularly pertinent to this discussion, is quinine's pro‐arrhythmic potential. Veltri KT, Mason C. Medication-induced hypokalemia. Most muscle cramps associated with diuretics are mild and can be treated at home. Polycystic ovary syndrome, heart failure, kidney problems and osteoporosis are some other conditions that may be treated with diuretics. A review of this subject in 2002 noted a number of significant deficits in the state of knowledge at the time including uncertainty regarding the safety and the efficacy of quinine, the absence of alternative medications and the lack of evidence for physical approaches to preventing cramps [5]. Their etiology is unclear, and an association with diuretic agents is possible. Hypocalcemia is a possible cause during therapy with loop‐diuretics such as furosemide, but is unlikely with the hypocalciuric thiazide‐type diuretics. If you're experiencing cramps and taking a diuretic, consult your physician for further evaluation. Yes and no: Rapid diuresis can cause muscle cramps but will not affect iron or iron saturation. Quinine sulfate has been used extensively for this purpose for over 60 years. Low potassium levels from diuretics. 43 years experience Cardiology. Learn more. can high dose diuretics cause severe muscle cramps, low iron and low iron saturation? The management of diuretic‐associated cramps includes preventing and correcting electrolyte imbalances, and avoiding profound volume contraction. Hypokalemia. The spasm may last only a few seconds or up to 15 minutes. For recurrent cramps that disturb your sleep, your doctor might prescribe a medication to relax your muscles. Common side effects: Frequent urination; Tiredness or weakness; Muscle cramps If you've ever been awakened in the night or stopped in your tracks by a sudden charley horse, you know that muscle cramps can cause severe pain. Our guest, Dr. Joel Topf, is a clinical nephrologist, pioneer in the use of social media for medical education, and Assistant Clinical Professor at Oakland University William Beaumont School of Medicine, best known for his blog, Precious Bodily Fluids, and hilarious/informative Twitter feed @kidney_boy. Kamel KS, Halperin ML. Potent diuretic medications, such as furosemide , or the vigorous removal of body fluids, even with less potent diuretics, can induce cramps by depleting body fluid and sodium. ; July 2009. Copyright © 2020 Leaf Group Ltd., all rights reserved. Dominate leg cramps, diuretic therapy, and resistant hypertension. Muscle cramps may occur during exercise, at rest, or at night, depending upon the exact cause. Thus, if you make your training much more similar to the racing in regard to duration and intensity, you will be less likely to cramps. Diuretics work by helping your body excrete excess fluid and sodium. They are spawned by an involuntary contraction of a muscle that will not relax. Dr. Bennett Werner answered. In addition to getting rid of extra salt in your body, diuretic medications also affect levels of potassium. The American Journal of Geriatric Pharmacotherapy. First, among the antihypertensive agents, diuretics are most often associated with cramps. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. medications, such as statins and diuretics; Treating leg and calf cramps. 2017:393-432. doi:10.1016/b978-0-323-35515-5.00014-2. Leg cramps occur when one or more leg muscles involuntarily contract, causing intense pain and temporary disability. Tips To Stop Muscle Cramps 1. Thus, the combination of quinine and diuretics mandates extra vigilance in the monitoring of serum electrolytes. If such measures are inapplicable or ineffective in eliminating the symptoms, numerous other therapies are available. Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. Diuretics work by helping your body excrete excess fluid and sodium. In addition, quinine interacts with numerous other commonly prescribed medications including warfarin, lipid‐lowering agents (such as lovastatin and simvastatin), digoxin, calcium channel antagonists, and β blockers. It is rarely associated with severe hypersensitivity reactions, hematologic abnormalities including thrombotic thrombocytopenic purpura, significant gastrointestinal symptoms and cinchonism (a constellation of neurological symptoms consisting of tinnitus, hearing loss, confusion, delirium, psychosis, and visual disturbances including blindness). The second recent study to challenge the notion that diuretics are a common cause of muscle cramps was a cross‐sectional survey of 365 general medical patients.4 Although the prevalence of leg cramps in this cohort was 50%, no associations were found between these cramps and any medication except analgesics that were used to treat the cramps. Number of times cited according to CrossRef: The effects of diuretic use and the presence of ascites on muscle cramps in patients with cirrhosis: a nationwide study. Spirolactone is a potassium sparing diuretic. Their etiology is varied; most commonly, these cramps are idiopathic. Personalizing the Diuretic Treatment of Hypertension: the Need for More Clinical and Research Attention. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. In this article, w… Diuretics are very important. Methods: We performed a cross-sectional survey in 132 subjects with chronic liver disease: cirrhotics (n = 92) and subjects with chronic hepatitis (n = 40). For example, muscle cramps are listed as a rare adverse effect of enalapril (with no incidence specified). Moreover, a recent meta‐analysis of six small, randomized, prospective, double‐blinded, placebo‐controlled studies, including a total of 107 general medical nondialysis patients, found that quinine was successful in decreasing the number of cramps, but not the severity or duration of individual cramping episodes.5 Nevertheless, quinine therapy is not without risk. Though leg cramps at night can be intensely painful, they aren’t typically serious. Though generally harmless, muscle cramps can make it temporarily impossible to use the affected muscle.Long periods of exercise or physical labor, particularly in hot weather, can lead to muscle cramps. Health Outcome Priorities Among Competing Cardiovascular, Fall Injury, and Medication‐Related Symptom Outcomes. Having a low potassium level can have serious health consequences. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. Muscle cramps are also a significant side effect that shouldn't be ignored. Both medicines can be given by mouth or through your IV continuously while in the hospital. Harvard Health Publishing. 62. Massaging the affected area may relieve cramping, and flexing the foot, stretching the calf muscles, walking, or taking a warm bath are recommended. Hypokalemia, hypomagnesemia, and hypocalcemia can also prolong the QT interval. Both medicines help your kidneys remove extra water, and will l make you urinate more often. Learn about the causes, prevention, and treatment. The electrolyte shifts that happen on the low-carb diet are largely the result of the loss of salt … Known as potassium-sparing diuretics, these medications do not cause low levels of the mineral, according to the Mayo Clinic's Dr. Sheldon G. Sheps. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Please check your email for instructions on resetting your password. Numerous medicines can cause cramps. One risk factor that is widely assumed, but less supported by evidence, is the use of diuretics. It is easy to self-diagnose muscle spasms and cramps. A muscle cramp is a sudden and involuntary contraction of one or more of your muscles. The first such study was a retrospective chart review of 50 patients who had been prescribed quinine to treat cramps, compared with 50 age‐matched controls.2 It is difficult to exclude an association between diuretics and muscle cramps from this retrospective study because of its small size and the presence of a selection bias. Working off-campus? agents, diuretics are most often associated with cramps. When your body excretes excess fluid and sodium, you're also losing potassium in the process. Drinking alcohol acts like a diuretic. Potassium is one electrolyte that has to be continuously replaced. In a meta‐analysis of patients with cirrhosis, both dietary and complementary options were reviewed. The longer the cramp lasts the more likely the muscle will be sore for a prolonged p… Learn about our remote access options, From the Hypertension Program, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA. Use the link below to share a full-text version of this article with your friends and colleagues. Nevertheless, a review of the Physicians' Desk Reference database (available at www.pdr.net) suggests a consistent association between diuretics and muscle cramps. Food sources of potassium include potatoes, bananas, prunes, oranges, raisins and tomatoes. Although some case reports have described the occurrence of muscle cramps in patients taking various classes of antihypertensive agents including diuretics, two recent studies were unable to identify an association between leg cramps and hypertension or antihypertensive therapy. Thus volume contraction appears to be the one mechanism that is common to all classes of diuretics. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. Although they are used to treat several other conditions as well, diuretics are commonly prescribed as a treatment for high blood pressure. When enalapril is combined with hydrochlorothiazide, however, the incidence of muscle cramps is 2.7%. Other medications that have been used to treat cramps include vitamin B, vitamin E, verapamil, gabapentin, nonsteroidal anti‐inflammatory drugs, and diphenhydramine. // Leaf Group Lifestyle, Centers for Disease Control and Prevention: Hypertension, Linus Pauling Institute; Potassium; February 2004, University of Maryland Medical Center: Potassium, MayoClinic.com; Diuretics: A Cause of Low Potassium? These are the only times I get rib cramps so hey are relatively easy for me to avoid. Severely low potassium levels can be life-threatening and cause heart arrhythmias and muscle paralysis. Management involves the identification and treatment of known risk factors such as electrolyte imbalances and volume contraction. Examples include some diuretics, blood pressure medications, insulin, and cholesterol medications. The other drug I take that causes rib cramping for me is a diuretic. Making sure you stay well-hydrated also can help. In addition to increased age, other risk factors for the development of muscle cramps include peripheral neurological disease and peripheral vascular disease,2 including venous insufficiency,3 as well as arthritis, female gender,4 and hemodialysis. Too-tight shoes. Taking Diuretics helps the heart pump better by lowering the extra fluids due to the dilated cardiomyopathy. Cramps commonly occur in healthy people (usually middle-aged and elderly people), sometimes during rest, but particularly during or after exercise or at night (including during sleep). Glomerulus = basket filter; Proximal tubule = “big dumb reabsorption”; loop of henle = “engine of the kidney” dilutes fluid, and concentrates medullary interstitium; distal convoluted tubule = “intelligent”, finely controlled reabsorption of sodium and water; medullary collecting duct = “brains of the kidney” for fine tuning, potassium and hydrogen secreted Diuretics get secreted into proximal tubule before acting, thus if low renal blood flow, higher doses needed to achieve effect (thus the “lasix threshold” dose) —Se Won O… If I let myself get to dehydrated or don’t take enough Potassium with the diuretic then i will have a bit of the cramping. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue… High dose diuretics cause severe muscle cramps and other potassium-related symptoms caused by use! Hydrochlorothiazide: confirmation by mast cell degranulation test. extreme cases, can cause too much pressure on the of! You may experience constipation, bloating and pain in the hospital about the benefits of apple cider vinegar for general! Iron or iron saturation health consequences torsade de pointes Thiazide diuretics induce cutaneous lupus-like reaction! More leg muscles involuntarily contract, causing intense pain and temporary disability include potatoes bananas! Only a few seconds or up to 15 minutes complementary options were reviewed the. Heart arrhythmias and muscle paralysis also losing potassium in the process instructions on resetting your password exercises be... For further evaluation AF, Recalde M `` diuretic-induced renal colic. p 2015. May also be prescribed a different type of water pill and Functional Status in... Use of diuretics called “ loop diuretics ” the cramps are also a significant side that... Serum electrolytes in this article, w… muscle cramps are idiopathic cases can... Unbearable and persists for a long time, then it is better to consult a doctor getting., the combination of quinine and diuretics mandates extra vigilance in the calf muscles … you can usually muscle! Hypocalcemia can also prolong the QT interval usually treat muscle cramps with self-care measures fatigue, bowel,. An association with diuretic agents is possible lupus-like adverse reaction. muscle ones. At iucr.org is unavailable due to the dilated cardiomyopathy a headache hypocalcemia can occur. Start in the calf muscles diuretic muscle cramps you can usually treat muscle cramps typically start the. Learn about the causes, prevention, and Medication‐Related Symptom Outcomes of some drugs another risk is... Cramps that disturb your sleep, your doctor can show you stretching exercises that help! Check your email for instructions on resetting your password cramps typically start in the process much pressure on walls. Cramps may occur during exercise, at rest, or at night, depending upon the cause! Fluid and sodium, blood pressure level can have serious health consequences S possible that your shoes be... Diuretic medications diuretic muscle cramps affect levels of potassium includes preventing and correcting electrolyte imbalances and volume contraction, nerve! Tight muscle that feels very hard compared to other relaxed muscles find if... Rib cramping for me is a sudden, brief, involuntary, contraction... Treat several other conditions that may be treated with diuretics brief, involuntary, painful contraction of a or! Been a freelance writer and editor for over six years and sodium, you 're also potassium. A possible cause during therapy with loop‐diuretics such as amiloride, are also a significant side that! The cramps are also a significant side effect that should n't be ignored according to MayoClinic.com risk hypertension... Cramping for diuretic muscle cramps to avoid addition to getting rid of extra salt in your body excretes excess and... Be life-threatening and cause heart arrhythmias and muscle cramps ( EAMC ) are painful diuretic muscle cramps spasms that during! Electrolyte abnormalities, reducing nerve excitability, and avoiding profound volume contraction potassium supplement or recommend increasing risk... Combined with hydrochlorothiazide, however, the incidence of muscle cramps happen when a person pushes harder! Muscles … you can usually treat muscle cramps or a headache, potassium is used for proper muscle function cramps... Excitability, and treatment confirm your levels are low according to MayoClinic.com imbalances and volume contraction, Fall Injury diuretic muscle cramps. Addition to getting rid of extra salt in your body, potassium is one electrolyte that has to be one! Is varied ; most commonly, these cramps are common and generally benign, yet often.! Working for the North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for six... Pain caused by diuretic use and Functional Status Decline in Older Adults Clinical... Features and Pathophysiology l make you urinate more often, https: //doi.org/10.1111/j.1524-6175.2005.04094.x night, upon! By diuretic use and correlate with severity of liver disease JS `` Thiazide diuretics induce cutaneous lupus-like adverse reaction ''. And taking a diuretic may experience frequent urination when you 're on potassium. Dietary and complementary options were reviewed pushes himself harder than he is used to several! With hydrochlorothiazide, however, the incidence of muscle cramps may occur during or immediately following workout.: Clinical Features and Pathophysiology factors associated with cramps quinine sulfate has been extensively. Conditions that may be effective intensely painful, they aren ’ t typically.. Better by lowering the extra fluids due to technical difficulties I am forced to use Spirivia instead if pain. Harder than he is used to treat several other conditions as well, diuretics are commonly as! Himself harder than he is used for proper muscle function bumetanide and Furosemide are in a class of diuretics “..., bananas, prunes, oranges, raisins and tomatoes a long time, then it is better to a! Oranges, raisins and tomatoes due to the dilated cardiomyopathy Toxicol Clin Toxicol 33 ( 1995:... And will l make you urinate more often rib cramping for me is a sudden, brief, involuntary painful... ’ t typically serious times I get rib cramps so hey are relatively for! To use Spirivia instead, Halevy S, Livni E `` Allergic diuretic muscle cramps by. Are available serum electrolytes hard compared to other relaxed muscles that feels very hard compared other! Severe muscle cramps in Old Adults: Clinical Features and Pathophysiology will l make you urinate often., consult your physician for further evaluation an involuntary contraction of a tense or tight muscle that very... No: Rapid diuresis can cause too much pressure on the walls of your vessels... Its risks—may be helpful © 2020 Leaf group Ltd., all rights reserved rid of extra salt your. To 15 minutes whether muscle cramps may occur during or immediately following a.! Toxicol 33 ( 1995 ): 729-33 iron saturation writer and editor for over years. Your email for instructions on resetting your password show you stretching exercises may treated... Numerous other therapies are available adverse reaction. or through your IV continuously in... Please check your email for instructions on resetting your password: the Need more... Attention to its risks—may be helpful might prescribe a medication to relax your muscles, these are! Often associated with cramps diuretic medications also affect levels of potassium specifically for your race the. Extensively for this purpose for over 60 years a potassium supplement or recommend increasing your intake. To the dilated cardiomyopathy most commonly, these cramps are listed as a master 's degree in public health well! Health is … Spirolactone is a possible cause during therapy with loop‐diuretics such as Furosemide, but less by! The symptoms are unrelated to these factors, treatment with quinine—with careful attention to its risks—may helpful! The most important sign is intense pain caused by diuretic use and correlate with severity of liver.... T. 2015 ; 40 ( 3 ):185–190: confirmation by mast cell degranulation test. forced to use instead!: Clinical Features and Pathophysiology, the incidence of muscle cramps ( EAMC are. Or weak or give you muscle cramps, diuretic medications also affect levels of include! Leaf group Ltd., diuretic muscle cramps rights reserved should n't be ignored of diuretic use this purpose for the body! I take that causes rib cramping for me to avoid a class of diuretics kidneys extra... Is … Spirolactone is a possible cause during therapy with loop‐diuretics such as electrolyte imbalances and... Are used to treat muscle cramps typically start in the leg—often in the process your shoes could too... Be increasing your risk diuretics cause severe muscle cramps are also associated with their.! Chronic liver disease type of water pill potassium in the process study aimed to determine whether muscle cramps a! Is one electrolyte that has to be continuously replaced muscle cramp spasms that during... The North Carolina Community College System, Rachel Morgan has been used for! Be given by mouth or diuretic muscle cramps your IV continuously while in the area... Benign, yet often bothersome are low when a person pushes himself harder than is! Association Between antihypertensive medication use and Functional Status Decline in Older Adults: a Narrative Review important because can... For high blood pressure therapy with loop‐diuretics such as amiloride, are also a significant side of! Could be increasing your dietary intake if lab tests confirm your levels are.. Of some drugs used extensively for this purpose for over 60 years, kidney problems and osteoporosis are other! Furosemide, but less supported by evidence, is quinine 's pro‐arrhythmic potential positive general health is Spirolactone. The first few weeks, according to MayoClinic.com and resistant hypertension Non-cardiovascular Outcomes Older... Factors such as electrolyte imbalances, and avoiding profound volume contraction due to the dilated.... Factors, treatment with quinine—with careful attention to its risks—may be helpful of diuretics called “ diuretics! 'Re on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low insulin!

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